Nio or NIO may refer to:
- Nio (Buddhism), guardians of the Buddha
 - Nio Inc., a Chinese electric automobile manufacturer
 - Nicaraguan córdoba, currency by ISO 4217 currency code
 - National Institute of Oceanography (disambiguation), several organizations
 - National Institute of Ophthalmology (disambiguation), several organizations
 - Neurotechnology Industry Organization
 - Non-blocking I/O (usually "NIO"), a collection of Java programming language APIs introduced with the J2SE 1.4 release of Java by Sun Microsystems
 - Northern Ireland Office, an arm of the United Kingdom government, responsible for Northern Ireland affairs
 - Nickel(II) oxide, NiO
 - Liang (surname), pronounced and romanized as Nio in several southern Chinese variants
 
See also
- Ios (aka: Nios, Greek: Νιός), an island in Greece
 - Nios (disambiguation)
 - Ni-0 zero-valent oxidation state, see nickel
 - All pages with titles beginning with NIO
 - All pages with titles beginning with Nio
 - All pages with titles containing nio
 - NLO (disambiguation)
 - N10 (disambiguation)
 
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