FIRS may refer to:
- Federal Inland Revenue Service, the federal tax administrator in Nigeria
 - Fédération Internationale de Roller Sports, the International Federation of Roller Sports
 - FIRS (index), a share index of the Banja Luka Stock Exchange
 - Forensic Investigation Research Station, a "body farm" at Colorado Mesa University
 - Forum of International Respiratory Societies, a respiratory health advocacy organization
 
See also
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