Alternative spellings include Daiane, Dianne, Dianna, Dian, Diahann, Dyan, Dyanne and Dyane. See also Di and Diana
Notable people
- Diane, Duchess of Württemberg (born 1940), French-German painter, sculptor, writer, and philanthropist
 - Diane Abbott (born 1953), British politician
 - Diane Austin-Broos (born 1946), Australian anthropologist
 - Diane Cummins (born 1974), Canadian middle-distance runner
 - Diane Damiano, American biomedical scientist and physical therapist
 - Diane D'Aquila (born 1952), Canadian-American actress
 - Diane Denoir (born 1957), Uruguayan singer
 - Diane Duane (born 1952), American writer
 - Diane Flacks, Canadian actress and writer
 - Diane de France (1538–1619), daughter of Henry II of France
 - Diane Franklin, American actress
 - Diane Gerace (born 1943), Canadian high jumper, long jumper, and pentathlete
 - Diane Guthrie-Gresham (born 1971), Jamaican long jumper and heptathlete
 - Diane Henderson, American applied mathematician
 - Diane Holl (born 1964), English motorsports engineer
 - Diane Keaton (born 1946), American actress
 - Diane Kennedy, American CPA, speaker and financial writer
 - Diane Kruger (born 1976), German actress
 - Diane Ladd (born 1935), American actress
 - Diane Lambert, American statistician
 - Diane Lane (born 1965), American actress
 - Diane S. Littler, American phycologist
 - Diane Maclagan (born 1974), mathematician
 - Diane Mazloum (born 1980), French-Lebanese writer
 - Diane Menzies, New Zealand landscape architect
 - Diane Modahl (born 1966), English middle-distance runner
 - Diane Murphy (born 1964), American actress
 - Diane Neal (born 1975), American actress
 - Diane Nelson (born 1958), Canadian curler
 - Diane Nelson (comics) (born 1968), American business executive
 - Diane Obomsawin (born 1959), Canadian author, illustrator and animated filmmaker
 - Diane Pappas (born 1970/1971), Democratic member of the Illinois House of Representatives
 - Diane de Poitiers (1500–1566), French noblewoman
 - Diane Rakiecki (born 1961), Canadian multi-sport para-athlete
 - Diane Ratnik (born 1962), Canadian volleyball player
 - Diane Sawyer (born 1945), American television journalist
 - Diane Tell (born 1959), Canadian musician
 - Diane Warren (born 1956), American songwriter
 - Diane von Furstenberg (born 1946), Belgian fashion designer
 - Diane Youdale (born 1970), English television personality
 
- Other
 
- Diahann Carroll (1935–2019), American actress and singer
 - Dian Fossey (1932–1985), American primatologist and conservationist
 - Dianne Nelson (born 1954), American short-story writer
 - Dyan Cannon (born 1937), American actress
 
Fictional characters
- Diane Court, a fictional character in the 1989 Cameron Crowe film Say Anything..., played by Ione Skye
 - Diane Chambers, a fictional character in the TV series Cheers
 - Diane Darcy, a fictional race car driver in Herbie Goes to Monte Carlo
 - Diane, an unseen character from the 2008 video game No More Heroes
 - Diane, an unseen and unheard character in the television show Twin Peaks
 - Diane Jenkins Newman, a character on the American soap opera The Young and the Restless
 - Diane Sugden, a character on the British soap opera Emmerdale
 - Diane Nguyen, a fictional character on the American adult animated series Bojack Horseman, voiced by Alison Brie
 - Pinkamena Diane Pie, full name of Pinkie Pie, a character in My Little Pony: Friendship is Magic
 - Diane Simmons, a character in the TV series Family Guy
 - Diane Johnson, a main character in Black-ish
 
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